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UPF1 regulates myeloid cell functions and S100A9 expression by the hnRNP E2/miRNA-328 balance

UPF1 is a key player in nonsense mediated mRNA decay (NMD) but also involved in posttranscriptional gene regulation. In this study we found that UPF1 regulates the expression of genes with functions in inflammation and myeloid cell differentiation via hnRNP E2. The majority of the UPF1-regulated gen...

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Detalles Bibliográficos
Autores principales: Saul, Meike J., Stein, Stefan, Grez, Manuel, Jakobsson, Per-Johan, Steinhilber, Dieter, Suess, Beatrix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004132/
https://www.ncbi.nlm.nih.gov/pubmed/27573788
http://dx.doi.org/10.1038/srep31995