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UPF1 regulates myeloid cell functions and S100A9 expression by the hnRNP E2/miRNA-328 balance
UPF1 is a key player in nonsense mediated mRNA decay (NMD) but also involved in posttranscriptional gene regulation. In this study we found that UPF1 regulates the expression of genes with functions in inflammation and myeloid cell differentiation via hnRNP E2. The majority of the UPF1-regulated gen...
Autores principales: | Saul, Meike J., Stein, Stefan, Grez, Manuel, Jakobsson, Per-Johan, Steinhilber, Dieter, Suess, Beatrix |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004132/ https://www.ncbi.nlm.nih.gov/pubmed/27573788 http://dx.doi.org/10.1038/srep31995 |
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