Epigenetic regulation of OAS2 shows disease-specific DNA methylation profiles at individual CpG sites

Epigenetic modifications are essential regulators of biological processes. Decreased DNA methylation of OAS2 (2′-5′-Oligoadenylate Synthetase 2), encoding an antiviral protein, has been seen in psoriasis. To provide further insight into the epigenetic regulation of OAS2, we performed pyrosequencing...

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Detalles Bibliográficos
Autores principales: Gu, Xiaolian, Boldrup, Linda, Coates, Philip J., Fahraeus, Robin, Nylander, Elisabet, Loizou, Christos, Olofsson, Katarina, Norberg-Spaak, Lena, Gärskog, Ola, Nylander, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004144/
https://www.ncbi.nlm.nih.gov/pubmed/27572959
http://dx.doi.org/10.1038/srep32579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004144/
https://www.ncbi.nlm.nih.gov/pubmed/27572959
http://dx.doi.org/10.1038/srep32579

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