Prions efficiently cross the intestinal barrier after oral administration: Study of the bioavailability, and cellular and tissue distribution in vivo

Natural forms of prion diseases frequently originate by oral (p.o.) infection. However, quantitative information on the gastro-intestinal (GI) absorption of prions (i.e. the bioavailability and subsequent biodistribution) is mostly unknown. The main goal of this study was to evaluate the fate of pri...

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Detalles Bibliográficos
Autores principales: Urayama, Akihiko, Concha-Marambio, Luis, Khan, Uffaf, Bravo-Alegria, Javiera, Kharat, Vineetkumar, Soto, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004172/
https://www.ncbi.nlm.nih.gov/pubmed/27573341
http://dx.doi.org/10.1038/srep32338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004172/
https://www.ncbi.nlm.nih.gov/pubmed/27573341
http://dx.doi.org/10.1038/srep32338

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