Polyurethane scaffolds seeded with CD34(+) cells maintain early stem cells whilst also facilitating prolonged egress of haematopoietic progenitors

We describe a 3D erythroid culture system that utilises a porous polyurethane (PU) scaffold to mimic the compartmentalisation found in the bone marrow. PU scaffolds seeded with peripheral blood CD34(+) cells exhibit a remarkable reproducibility of egress, with an increased output when directly compa...

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Detalles Bibliográficos
Autores principales: Severn, Charlotte E., Macedo, Hugo, Eagle, Mark J., Rooney, Paul, Mantalaris, Athanasios, Toye, Ashley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004174/
https://www.ncbi.nlm.nih.gov/pubmed/27573994
http://dx.doi.org/10.1038/srep32149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004174/
https://www.ncbi.nlm.nih.gov/pubmed/27573994
http://dx.doi.org/10.1038/srep32149

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