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Presynaptic DLG regulates synaptic function through the localization of voltage-activated Ca(2+) Channels

The DLG-MAGUK subfamily of proteins plays a role on the recycling and clustering of glutamate receptors (GLUR) at the postsynaptic density. discs-large1 (dlg) is the only DLG-MAGUK gene in Drosophila and originates two main products, DLGA and DLGS97 which differ by the presence of an L27 domain. Com...

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Detalles Bibliográficos
Autores principales: Astorga, César, Jorquera, Ramón A., Ramírez, Mauricio, Kohler, Andrés, López, Estefanía, Delgado, Ricardo, Córdova, Alex, Olguín, Patricio, Sierralta, Jimena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004195/
https://www.ncbi.nlm.nih.gov/pubmed/27573697
http://dx.doi.org/10.1038/srep32132