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Anti-proliferative and cytotoxic activity of rosuvastatin against melanoma cells

INTRODUCTION: Statins are considered potential candidate agents for melanoma chemoprevention. Statin-induced mevalonate pathway inhibition leads to reduction of cholesterol synthesis and also to decreased cellular levels of non-steroidal isoprenoids, geranylgeranyl pyrophosphate and farnesyl pyropho...

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Detalles Bibliográficos
Autores principales: Maj, Malgorzata, Czajkowski, Rafal, Zegarska, Barbara, Kowaliszyn, Bogna, Pokrywczynska, Marta, Drewa, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004214/
https://www.ncbi.nlm.nih.gov/pubmed/27605895
http://dx.doi.org/10.5114/ada.2016.61601