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Anti-proliferative and cytotoxic activity of rosuvastatin against melanoma cells
INTRODUCTION: Statins are considered potential candidate agents for melanoma chemoprevention. Statin-induced mevalonate pathway inhibition leads to reduction of cholesterol synthesis and also to decreased cellular levels of non-steroidal isoprenoids, geranylgeranyl pyrophosphate and farnesyl pyropho...
Autores principales: | Maj, Malgorzata, Czajkowski, Rafal, Zegarska, Barbara, Kowaliszyn, Bogna, Pokrywczynska, Marta, Drewa, Tomasz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004214/ https://www.ncbi.nlm.nih.gov/pubmed/27605895 http://dx.doi.org/10.5114/ada.2016.61601 |
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