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Biosynthesis of phlorisovalerophenone and 4-hydroxy-6-isobutyl-2-pyrone in Escherichia coli from glucose

BACKGROUND: Type III polyketide synthases (PKSs) contribute to the synthesis of many economically important natural products, which are typically produced by direct extraction from plants or synthesized chemically. For example, humulone and lupulone (Fig. 1a) in hops (Humulus lupulus) account for th...

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Detalles Bibliográficos
Autores principales: Zhou, Wei, Zhuang, Yibin, Bai, Yanfen, Bi, Huiping, Liu, Tao, Ma, Yanhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004256/
https://www.ncbi.nlm.nih.gov/pubmed/27577056
http://dx.doi.org/10.1186/s12934-016-0549-9