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Biosynthesis of phlorisovalerophenone and 4-hydroxy-6-isobutyl-2-pyrone in Escherichia coli from glucose
BACKGROUND: Type III polyketide synthases (PKSs) contribute to the synthesis of many economically important natural products, which are typically produced by direct extraction from plants or synthesized chemically. For example, humulone and lupulone (Fig. 1a) in hops (Humulus lupulus) account for th...
Autores principales: | Zhou, Wei, Zhuang, Yibin, Bai, Yanfen, Bi, Huiping, Liu, Tao, Ma, Yanhe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004256/ https://www.ncbi.nlm.nih.gov/pubmed/27577056 http://dx.doi.org/10.1186/s12934-016-0549-9 |
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