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Construction of a Multiplex Promoter Reporter Platform to Monitor Staphylococcus aureus Virulence Gene Expression and the Identification of Usnic Acid as a Potent Suppressor of psm Gene Expression

As antibiotic resistance becomes phenomenal, alternative therapeutic strategies for bacterial infections such as anti-virulence treatments have been advocated. We have constructed a total of 20 gfp-luxABCDE dual-reporter plasmids with selected promoters from S. aureus virulence-associated genes. The...

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Detalles Bibliográficos
Autores principales: Gao, Peng, Wang, Yanli, Villanueva, Iván, Ho, Pak Leung, Davies, Julian, Kao, Richard Yi Tsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004274/
https://www.ncbi.nlm.nih.gov/pubmed/27625639
http://dx.doi.org/10.3389/fmicb.2016.01344