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Early infiltration of p40IL12(+)CCR7(+)CD11b(+) cells is critical for fibrosis development

INTRODUCTION: Macrophages are heterogeneous and thus can be correlated with distinct tissue outcomes after injury. Conflicting data have indicated that the M2‐related phenotype directly triggers fibrosis. Conversely, we hypothesize here that the inflammatory milieu provided by early infiltration of...

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Detalles Bibliográficos
Autores principales: Braga, Tarcio Teodoro, Correa‐Costa, Matheus, Azevedo, Hatylas, Silva, Reinaldo Correia, Cruz, Mario Costa, Almeida, Maira Estanislau Soares, Hiyane, Meire Ioshie, Moreira‐Filho, Carlos Alberto, Santos, Marinilce Fagundes, Perez, Katia Regina, Cuccovia, Iolanda Midea, Camara, Niels Olsen Saraiva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004285/
https://www.ncbi.nlm.nih.gov/pubmed/27621813
http://dx.doi.org/10.1002/iid3.114