The blocking of uPAR suppresses lipopolysaccharide‐induced inflammatory osteoclastogenesis and the resultant bone loss through attenuation of integrin β3/Akt pathway

INTRODUCTION: Chronic inflammatory diseases, such as rheumatoid arthritis and periodontitis, cause the bone destruction by promotion of the differentiation of monocyte/macrophage lineage cells into mature osteoclasts (OCs) with active bone‐resorbing character. However, the detailed mechanisms underl...

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Detalles Bibliográficos
Autores principales: Kanno, Yosuke, Ishisaki, Akira, Miyashita, Mei, Matsuo, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004288/
https://www.ncbi.nlm.nih.gov/pubmed/27621816
http://dx.doi.org/10.1002/iid3.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004288/
https://www.ncbi.nlm.nih.gov/pubmed/27621816
http://dx.doi.org/10.1002/iid3.116

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