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Cholesterol‐sensing liver X receptors stimulate Th2‐driven allergic eosinophilic asthma in mice

INTRODUCTION: Liver X receptors (LXRs) are nuclear receptors that function as cholesterol sensors and regulate cholesterol homeostasis. High cholesterol has been recognized as a risk factor in asthma; however, the mechanism of this linkage is not known. METHODS: To explore the importance of choleste...

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Detalles Bibliográficos
Autores principales: Smet, Muriel, Van Hoecke, Lien, De Beuckelaer, Ans, Vander Beken, Seppe, Naessens, Thomas, Vergote, Karl, Willart, Monique, Lambrecht, Bart N., Gustafsson, Jan‐Åke, Steffensen, Knut R., Grooten, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004289/
https://www.ncbi.nlm.nih.gov/pubmed/27621817
http://dx.doi.org/10.1002/iid3.118