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Cholesterol‐sensing liver X receptors stimulate Th2‐driven allergic eosinophilic asthma in mice
INTRODUCTION: Liver X receptors (LXRs) are nuclear receptors that function as cholesterol sensors and regulate cholesterol homeostasis. High cholesterol has been recognized as a risk factor in asthma; however, the mechanism of this linkage is not known. METHODS: To explore the importance of choleste...
Autores principales: | Smet, Muriel, Van Hoecke, Lien, De Beuckelaer, Ans, Vander Beken, Seppe, Naessens, Thomas, Vergote, Karl, Willart, Monique, Lambrecht, Bart N., Gustafsson, Jan‐Åke, Steffensen, Knut R., Grooten, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004289/ https://www.ncbi.nlm.nih.gov/pubmed/27621817 http://dx.doi.org/10.1002/iid3.118 |
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