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IFN‐λ3 polymorphism indirectly influences NK cell phenotype and function during acute HCV infection

INTRODUCTION: Polymorphisms in the type III interferon IFN‐λ3 and the killer cell immunoglobulin‐like receptor (KIR) genes controlling the activity of natural killer (NK) cells can predict spontaneous resolution of acute hepatitis C virus (HCV) infection. We hypothesized that IFN‐λ3 polymorphism may...

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Detalles Bibliográficos
Autores principales: Depla, Marion, Pelletier, Sandy, Bédard, Nathalie, Brunaud, Camille, Bruneau, Julie, Shoukry, Naglaa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004291/
https://www.ncbi.nlm.nih.gov/pubmed/27621819
http://dx.doi.org/10.1002/iid3.122