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Dual regulation of the native ClC-K2 chloride channel in the distal nephron by voltage and pH

ClC-K2, a member of the ClC family of Cl(−) channels and transporters, forms the major basolateral Cl(−) conductance in distal nephron epithelial cells and therefore plays a central role in renal Cl(−) absorption. However, its regulation remains largely unknown because of the fact that recombinant C...

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Detalles Bibliográficos
Autores principales: Pinelli, Laurent, Nissant, Antoine, Edwards, Aurélie, Lourdel, Stéphane, Teulon, Jacques, Paulais, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004338/
https://www.ncbi.nlm.nih.gov/pubmed/27574292
http://dx.doi.org/10.1085/jgp.201611623