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Multiciliated cell basal bodies align in stereotypical patterns coordinated by the apical cytoskeleton

Multiciliated cells (MCCs) promote fluid flow through coordinated ciliary beating, which requires properly organized basal bodies (BBs). Airway MCCs have large numbers of BBs, which are uniformly oriented and, as we show here, align linearly. The mechanism for BB alignment is unexplored. To study th...

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Detalles Bibliográficos
Autores principales: Herawati, Elisa, Taniguchi, Daisuke, Kanoh, Hatsuho, Tateishi, Kazuhiro, Ishihara, Shuji, Tsukita, Sachiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004441/
https://www.ncbi.nlm.nih.gov/pubmed/27573463
http://dx.doi.org/10.1083/jcb.201601023