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Septins promote macropinosome maturation and traffic to the lysosome by facilitating membrane fusion
Macropinocytosis, the internalization of extracellular fluid and material by plasma membrane ruffles, is critical for antigen presentation, cell metabolism, and signaling. Macropinosomes mature through homotypic and heterotypic fusion with endosomes and ultimately merge with lysosomes. The molecular...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004444/ https://www.ncbi.nlm.nih.gov/pubmed/27551056 http://dx.doi.org/10.1083/jcb.201603030 |