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CRISPR-Cas9 nuclear dynamics and target recognition in living cells

The bacterial CRISPR-Cas9 system has been repurposed for genome engineering, transcription modulation, and chromosome imaging in eukaryotic cells. However, the nuclear dynamics of clustered regularly interspaced short palindromic repeats (CRISPR)–associated protein 9 (Cas9) guide RNAs and target int...

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Detalles Bibliográficos
Autores principales: Ma, Hanhui, Tu, Li-Chun, Naseri, Ardalan, Huisman, Maximiliaan, Zhang, Shaojie, Grunwald, David, Pederson, Thoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004447/
https://www.ncbi.nlm.nih.gov/pubmed/27551060
http://dx.doi.org/10.1083/jcb.201604115