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Loss of function of the Drosophila Ninein-related centrosomal protein Bsg25D causes mitotic defects and impairs embryonic development

The centrosome-associated proteins Ninein (Nin) and Ninein-like protein (Nlp) play significant roles in microtubule stability, nucleation and anchoring at the centrosome in mammalian cells. Here, we investigate Blastoderm specific gene 25D (Bsg25D), which encodes the only Drosophila protein that is...

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Detalles Bibliográficos
Autores principales: Kowanda, Michelle, Bergalet, Julie, Wieczorek, Michal, Brouhard, Gary, Lécuyer, Éric, Lasko, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004617/
https://www.ncbi.nlm.nih.gov/pubmed/27422905
http://dx.doi.org/10.1242/bio.019638