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p53 directly regulates the glycosidase FUCA1 to promote chemotherapy-induced cell death

p53 is a central factor in tumor suppression as exemplified by its frequent loss in human cancer. p53 exerts its tumor suppressive effects in multiple ways, but the ability to invoke the eradication of damaged cells by programmed cell death is considered a key factor. The ways in which p53 promotes...

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Detalles Bibliográficos
Autores principales: Baudot, Alice D., Crighton, Diane, O'Prey, Jim, Somers, Joanna, Sierra Gonzalez, Pablo, Ryan, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004703/
https://www.ncbi.nlm.nih.gov/pubmed/27315169
http://dx.doi.org/10.1080/15384101.2016.1191714