Cargando…
p53 directly regulates the glycosidase FUCA1 to promote chemotherapy-induced cell death
p53 is a central factor in tumor suppression as exemplified by its frequent loss in human cancer. p53 exerts its tumor suppressive effects in multiple ways, but the ability to invoke the eradication of damaged cells by programmed cell death is considered a key factor. The ways in which p53 promotes...
Autores principales: | Baudot, Alice D., Crighton, Diane, O'Prey, Jim, Somers, Joanna, Sierra Gonzalez, Pablo, Ryan, Kevin M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004703/ https://www.ncbi.nlm.nih.gov/pubmed/27315169 http://dx.doi.org/10.1080/15384101.2016.1191714 |
Ejemplares similares
-
p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death
por: Long, J S, et al.
Publicado: (2015) -
FUCA1 is induced by wild-type p53 and expressed at different levels in thyroid cancers depending on p53 status
Publicado: (2017) -
Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cells
por: Bennett, H L, et al.
Publicado: (2010) -
mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux
por: Beaumatin, Florian, et al.
Publicado: (2019) -
DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose
por: Mrschtik, M, et al.
Publicado: (2015)