Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity

Limb-specific Shh expression is regulated by the (∼1 Mb distant) ZRS enhancer. In the mouse, limb bud-restricted spatiotemporal Shh expression occurs from ∼E10 to E11.5 at the distal posterior margin and is essential for correct autopod formation. Here, we have analysed the higher-order chromatin co...

Descripción completa

Detalles Bibliográficos
Autores principales: Williamson, Iain, Lettice, Laura A., Hill, Robert E., Bickmore, Wendy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004883/
https://www.ncbi.nlm.nih.gov/pubmed/27402708
http://dx.doi.org/10.1242/dev.139188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004883/
https://www.ncbi.nlm.nih.gov/pubmed/27402708
http://dx.doi.org/10.1242/dev.139188

Ejemplares similares