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Crucial roles of the Arp2/3 complex during mammalian corticogenesis

The polarity and organization of radial glial cells (RGCs), which serve as both stem cells and scaffolds for neuronal migration, are crucial for cortical development. However, the cytoskeletal mechanisms that drive radial glial outgrowth and maintain RGC polarity remain poorly understood. Here, we s...

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Detalles Bibliográficos
Autores principales: Wang, Pei-Shan, Chou, Fu-Sheng, Ramachandran, Sreekumar, Xia, Sheng, Chen, Huei-Ying, Guo, Fengli, Suraneni, Praveen, Maher, Brady J., Li, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004905/
https://www.ncbi.nlm.nih.gov/pubmed/27385014
http://dx.doi.org/10.1242/dev.130542