Single-molecule RNA detection at depth by hybridization chain reaction and tissue hydrogel embedding and clearing

Accurate and robust detection of mRNA molecules in thick tissue samples can reveal gene expression patterns in single cells within their native environment. Preserving spatial relationships while accessing the transcriptome of selected cells is a crucial feature for advancing many biological areas –...

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Detalles Bibliográficos
Autores principales: Shah, Sheel, Lubeck, Eric, Schwarzkopf, Maayan, He, Ting-Fang, Greenbaum, Alon, Sohn, Chang Ho, Lignell, Antti, Choi, Harry M. T., Gradinaru, Viviana, Pierce, Niles A., Cai, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Techniques and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004914/
https://www.ncbi.nlm.nih.gov/pubmed/27342713
http://dx.doi.org/10.1242/dev.138560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004914/
https://www.ncbi.nlm.nih.gov/pubmed/27342713
http://dx.doi.org/10.1242/dev.138560

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