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Oxygen Partial Pressure Is a Rate-Limiting Parameter for Cell Proliferation in 3D Spheroids Grown in Physioxic Culture Condition

The in situ oxygen partial pressure in normal and tumor tissues is in the range of a few percent. Therefore, when studying cell growth in 3D culture systems, it is essential to consider how the physiological oxygen concentration, rather than the one in the ambient air, influences the proliferation p...

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Detalles Bibliográficos
Autores principales: Gomes, Aurélie, Guillaume, Ludivine, Grimes, David Robert, Fehrenbach, Jérôme, Lobjois, Valérie, Ducommun, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004916/
https://www.ncbi.nlm.nih.gov/pubmed/27575790
http://dx.doi.org/10.1371/journal.pone.0161239