Noninvasive monitoring of the genetic evolution of EGFR-mutant non-small-cell lung cancer by analyzing circulating tumor DNA during combination chemotherapy with gefitinib and pemetrexed or S-1

BACKGROUND: Repetitive genotyping is useful to assess the genetic evolution of non-small-cell lung cancer (NSCLC) during treatment, but the need for sampling by biopsy is a major obstacle. Digital polymerase chain reaction (PCR) is a promising procedure for the detection of mutant alleles in plasma...

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Detalles Bibliográficos
Autores principales: Nakahara, Yoshiro, Takagi, Yusuke, Hosomi, Yukio, Kagei, Akiko, Yamamoto, Tomohiro, Sawada, Takeshi, Yomota, Makiko, Okuma, Yusuke, Mikura, Shinichiro, Okamura, Tatsuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Clinical Trial Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004997/
https://www.ncbi.nlm.nih.gov/pubmed/27601920
http://dx.doi.org/10.2147/OTT.S105976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004997/
https://www.ncbi.nlm.nih.gov/pubmed/27601920
http://dx.doi.org/10.2147/OTT.S105976

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