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Noninvasive monitoring of the genetic evolution of EGFR-mutant non-small-cell lung cancer by analyzing circulating tumor DNA during combination chemotherapy with gefitinib and pemetrexed or S-1

BACKGROUND: Repetitive genotyping is useful to assess the genetic evolution of non-small-cell lung cancer (NSCLC) during treatment, but the need for sampling by biopsy is a major obstacle. Digital polymerase chain reaction (PCR) is a promising procedure for the detection of mutant alleles in plasma...

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Detalles Bibliográficos
Autores principales:	Nakahara, Yoshiro, Takagi, Yusuke, Hosomi, Yukio, Kagei, Akiko, Yamamoto, Tomohiro, Sawada, Takeshi, Yomota, Makiko, Okuma, Yusuke, Mikura, Shinichiro, Okamura, Tatsuru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Clinical Trial Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004997/ https://www.ncbi.nlm.nih.gov/pubmed/27601920 http://dx.doi.org/10.2147/OTT.S105976

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