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Histidine phosphorylation relieves copper inhibition in the mammalian potassium channel KCa3.1

KCa2.1, KCa2.2, KCa2.3 and KCa3.1 constitute a family of mammalian small- to intermediate-conductance potassium channels that are activated by calcium-calmodulin. KCa3.1 is unique among these four channels in that activation requires, in addition to calcium, phosphorylation of a single histidine res...

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Detalles Bibliográficos
Autores principales: Srivastava, Shekhar, Panda, Saswati, Li, Zhai, Fuhs, Stephen R, Hunter, Tony, Thiele, Dennis J, Hubbard, Stevan R, Skolnik, Edward Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005030/
https://www.ncbi.nlm.nih.gov/pubmed/27542194
http://dx.doi.org/10.7554/eLife.16093