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VAC chemotherapy with valproic acid for refractory/relapsing small cell lung cancer: a phase II study
Salvage chemotherapy (CT) for relapsing or refractory small cell lung cancer (SCLC) remains disappointing. In vitro experiments showed that valproic acid increases apoptosis of SCLC cell lines exposed to doxorubicin, vindesine and bis(2-chloroethyl)amine. The primary objective of this phase II study...
Autores principales: | Berghmans, Thierry, Lafitte, Jean-Jacques, Scherpereel, Arnaud, Ameye, Lieveke, Paesmans, Marianne, Meert, Anne-Pascale, Colinet, Benoit, Tulippe, Christian, Willems, Luc, Leclercq, Nathalie, Sculier, Jean-Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005117/ https://www.ncbi.nlm.nih.gov/pubmed/27730152 http://dx.doi.org/10.1183/23120541.00029-2015 |
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