Niclosamide suppresses renal cell carcinoma by inhibiting Wnt/β-catenin and inducing mitochondrial dysfunctions

PURPOSE: To investigate the effects of anthelminthic drug niclosamide in renal cell carcinoma (RCC) and the underlying mechanisms of its action. METHODS: The effects of niclosamide on the proliferation and apoptosis of RCC cells were examined in vitro and in vivo by using MTS, colony formation assay...

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Detalles Bibliográficos
Autores principales: Zhao, Juan, He, Qiushan, Gong, Zhimin, Chen, Sen, Cui, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005241/
https://www.ncbi.nlm.nih.gov/pubmed/27652012
http://dx.doi.org/10.1186/s40064-016-3153-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005241/
https://www.ncbi.nlm.nih.gov/pubmed/27652012
http://dx.doi.org/10.1186/s40064-016-3153-x

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