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Niclosamide suppresses renal cell carcinoma by inhibiting Wnt/β-catenin and inducing mitochondrial dysfunctions

PURPOSE: To investigate the effects of anthelminthic drug niclosamide in renal cell carcinoma (RCC) and the underlying mechanisms of its action. METHODS: The effects of niclosamide on the proliferation and apoptosis of RCC cells were examined in vitro and in vivo by using MTS, colony formation assay...

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Detalles Bibliográficos
Autores principales:	Zhao, Juan, He, Qiushan, Gong, Zhimin, Chen, Sen, Cui, Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005241/ https://www.ncbi.nlm.nih.gov/pubmed/27652012 http://dx.doi.org/10.1186/s40064-016-3153-x

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