Amplified in Breast Cancer Regulates Transcription and Translation in Breast Cancer Cells

BACKGROUND: Control of mRNA translation is fundamentally altered in cancer. Insulin-like growth factor-I (IGF-I) signaling regulates key translation mediators to modulate protein synthesis (e.g. eIF4E, 4E-BP1, mTOR, and S6K1). Importantly the Amplified in Breast Cancer (AIB1) oncogene regulates tran...

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Detalles Bibliográficos
Autores principales: Ochnik, Aleksandra M., Peterson, Mark S., Avdulov, Svetlana V., Oh, Annabell S., Bitterman, Peter B., Yee, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005264/
https://www.ncbi.nlm.nih.gov/pubmed/26936396
http://dx.doi.org/10.1016/j.neo.2016.01.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005264/
https://www.ncbi.nlm.nih.gov/pubmed/26936396
http://dx.doi.org/10.1016/j.neo.2016.01.001

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