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Unique Footprint in the scl1.3 Locus Affects Adhesion and Biofilm Formation of the Invasive M3-Type Group A Streptococcus

The streptococcal collagen-like proteins 1 and 2 (Scl1 and Scl2) are major surface adhesins that are ubiquitous among group A Streptococcus (GAS). Invasive M3-type strains, however, have evolved two unique conserved features in the scl1 locus: (i) an IS1548 element insertion in the scl1 promoter reg...

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Detalles Bibliográficos
Autores principales: Bachert, Beth A., Choi, Soo J., LaSala, Paul R., Harper, Tiffany I., McNitt, Dudley H., Boehm, Dylan T., Caswell, Clayton C., Ciborowski, Pawel, Keene, Douglas R., Flores, Anthony R., Musser, James M., Squeglia, Flavia, Marasco, Daniela, Berisio, Rita, Lukomski, Slawomir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005324/
https://www.ncbi.nlm.nih.gov/pubmed/27630827
http://dx.doi.org/10.3389/fcimb.2016.00090