The Influence of Copy-Number of Targeted Extrachromosomal Genetic Elements on the Outcome of CRISPR-Cas Defense

Prokaryotic type I CRISPR-Cas systems respond to the presence of mobile genetic elements such as plasmids and phages in two different ways. CRISPR interference efficiently destroys foreign DNA harboring protospacers fully matching CRISPR RNA spacers. In contrast, even a single mismatch between a spa...

Descripción completa

Detalles Bibliográficos
Autores principales: Severinov, Konstantin, Ispolatov, Iaroslav, Semenova, Ekaterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005344/
https://www.ncbi.nlm.nih.gov/pubmed/27630990
http://dx.doi.org/10.3389/fmolb.2016.00045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005344/
https://www.ncbi.nlm.nih.gov/pubmed/27630990
http://dx.doi.org/10.3389/fmolb.2016.00045

Ejemplares similares