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Changes in the Transcriptome of Human Astrocytes Accompanying Oxidative Stress-Induced Senescence

Aging is a major risk factor for many neurodegenerative disorders. A key feature of aging biology that may underlie these diseases is cellular senescence. Senescent cells accumulate in tissues with age, undergo widespread changes in gene expression, and typically demonstrate altered, pro-inflammator...

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Detalles Bibliográficos
Autores principales: Crowe, Elizabeth P., Tuzer, Ferit, Gregory, Brian D., Donahue, Greg, Gosai, Sager J., Cohen, Justin, Leung, Yuk Y., Yetkin, Emre, Nativio, Raffaella, Wang, Li-San, Sell, Christian, Bonini, Nancy M., Berger, Shelley L., Johnson, F. Brad, Torres, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005348/
https://www.ncbi.nlm.nih.gov/pubmed/27630559
http://dx.doi.org/10.3389/fnagi.2016.00208