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Total ginsenosides suppress monocrotaline-induced pulmonary hypertension in rats: involvement of nitric oxide and mitogen-activated protein kinase pathways

BACKGROUND: Ginsenosides have been shown to exert beneficial pharmacological effects on the central nervous, cardiovascular, and endocrine systems. We sought to determine whether total ginsenosides (TG) inhibit monocrotaline (MCT)-induced pulmonary hypertension and to elucidate the underlying mechan...

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Detalles Bibliográficos
Autores principales: Qin, Na, Yang, Wei, Feng, Dongxu, Wang, Xinwen, Qi, Muyao, Du, Tianxin, Sun, Hongzhi, Wu, Shufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005363/
https://www.ncbi.nlm.nih.gov/pubmed/27616905
http://dx.doi.org/10.1016/j.jgr.2015.09.005