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Total ginsenosides suppress monocrotaline-induced pulmonary hypertension in rats: involvement of nitric oxide and mitogen-activated protein kinase pathways
BACKGROUND: Ginsenosides have been shown to exert beneficial pharmacological effects on the central nervous, cardiovascular, and endocrine systems. We sought to determine whether total ginsenosides (TG) inhibit monocrotaline (MCT)-induced pulmonary hypertension and to elucidate the underlying mechan...
Autores principales: | Qin, Na, Yang, Wei, Feng, Dongxu, Wang, Xinwen, Qi, Muyao, Du, Tianxin, Sun, Hongzhi, Wu, Shufang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005363/ https://www.ncbi.nlm.nih.gov/pubmed/27616905 http://dx.doi.org/10.1016/j.jgr.2015.09.005 |
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