Profile of Antiemetic Activity of Netupitant Alone or in Combination with Palonosetron and Dexamethasone in Ferrets and Suncus murinus (House Musk Shrew)

Background and Aims: Chemotherapy-induced acute and delayed emesis involves the activation of multiple pathways, with 5-hydroxytryptamine (5-HT; serotonin) playing a major role in the initial response. Substance P tachykinin NK(1) receptor antagonists can reduce emesis induced by disparate emetic ch...

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Detalles Bibliográficos
Autores principales: Rudd, John A., Ngan, Man P., Lu, Zengbing, Higgins, Guy A., Giuliano, Claudio, Lovati, Emanuela, Pietra, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005416/
https://www.ncbi.nlm.nih.gov/pubmed/27630563
http://dx.doi.org/10.3389/fphar.2016.00263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005416/
https://www.ncbi.nlm.nih.gov/pubmed/27630563
http://dx.doi.org/10.3389/fphar.2016.00263

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