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Profile of Antiemetic Activity of Netupitant Alone or in Combination with Palonosetron and Dexamethasone in Ferrets and Suncus murinus (House Musk Shrew)
Background and Aims: Chemotherapy-induced acute and delayed emesis involves the activation of multiple pathways, with 5-hydroxytryptamine (5-HT; serotonin) playing a major role in the initial response. Substance P tachykinin NK(1) receptor antagonists can reduce emesis induced by disparate emetic ch...
Autores principales: | Rudd, John A., Ngan, Man P., Lu, Zengbing, Higgins, Guy A., Giuliano, Claudio, Lovati, Emanuela, Pietra, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005416/ https://www.ncbi.nlm.nih.gov/pubmed/27630563 http://dx.doi.org/10.3389/fphar.2016.00263 |
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