Effect of HSV-IL12 Loaded Tumor Cell-Based Vaccination in a Mouse Model of High-Grade Neuroblastoma

We designed multimodal tumor vaccine that consists of irradiated tumor cells infected with the oncolytic IL-12-expressing HSV-1 virus, M002. This vaccine was tested against the syngeneic neuroblastoma mouse model Neuro 2a injected into the right caudate nucleus of the immunocompetent A/J mice. Mice...

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Detalles Bibliográficos
Autores principales: Bauer, David F., Pereboeva, Larisa, Gillespie, G. Yancey, Cloud, Gretchen A., Elzafarany, Osama, Langford, Catherine, Markert, James M., Jr., Lawrence S. Lamb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005549/
https://www.ncbi.nlm.nih.gov/pubmed/27610392
http://dx.doi.org/10.1155/2016/2568125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005549/
https://www.ncbi.nlm.nih.gov/pubmed/27610392
http://dx.doi.org/10.1155/2016/2568125

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