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A Cross-Sectional Comparison of Druggable Mutations in Primary Tumors, Metastatic Tissue, Circulating Tumor Cells, and Cell-Free Circulating DNA in Patients with Metastatic Breast Cancer: The MIRROR Study Protocol

BACKGROUND: Characterization of the driver mutations in an individual metastatic breast cancer (MBC) patient is critical to selecting effective targeted therapies. Currently, it is believed that the limited efficacy of many targeted drugs may be due to the expansion of drug resistant clones with dif...

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Detalles Bibliográficos
Autores principales: Gonzalez-Rivera, Milagros, Picornell, Antoni C, Alvarez, Enrique L, Martin, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005674/
https://www.ncbi.nlm.nih.gov/pubmed/27531554
http://dx.doi.org/10.2196/resprot.6024