Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice

Single nucleotide polymorphisms (SNPs) close to the VPS13C, C2CD4A and C2CD4B genes on chromosome 15q are associated with impaired fasting glucose and increased risk of type 2 diabetes. eQTL analysis revealed an association between possession of risk (C) alleles at a previously implicated causal SNP...

Descripción completa

Detalles Bibliográficos
Autores principales: Mehta, Zenobia B., Fine, Nicholas, Pullen, Timothy J., Cane, Matthew C., Hu, Ming, Chabosseau, Pauline, Meur, Gargi, Velayos-Baeza, Antonio, Monaco, Anthony P., Marselli, Lorella, Marchetti, Piero, Rutter, Guy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2016
Materias:
Call for Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005967/
https://www.ncbi.nlm.nih.gov/pubmed/27329800
http://dx.doi.org/10.1152/ajpendo.00074.2016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005967/
https://www.ncbi.nlm.nih.gov/pubmed/27329800
http://dx.doi.org/10.1152/ajpendo.00074.2016

Ejemplares similares