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Sensitive detection of miRNA by using hybridization chain reaction coupled with positively charged gold nanoparticles

Positively charged gold nanoparticles (+)AuNPs can adsorb onto the negatively charged surface of single-stranded DNA (ssDNA) or double-stranded DNA (dsDNA). Herein, long-range dsDNA polymers could form based on the hybridization chain reaction (HCR) of two hairpin probes (H(1) and H(2)) by using miR...

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Detalles Bibliográficos
Autores principales: Miao, Xiangmin, Ning, Xue, Li, Zongbing, Cheng, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006024/
https://www.ncbi.nlm.nih.gov/pubmed/27576601
http://dx.doi.org/10.1038/srep32358