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Drosophila Dullard functions as a Mad phosphatase to terminate BMP signaling

Bone morphogenetic proteins (BMPs) are growth factors that provide essential signals for normal embryonic development and adult tissue homeostasis. A key step in initiating BMP signaling is ligand induced phosphorylation of receptor Smads (R-Smads) by type I receptor kinases, while linker phosphoryl...

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Detalles Bibliográficos
Autores principales: Urrutia, Hugo, Aleman, Abigail, Eivers, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006046/
https://www.ncbi.nlm.nih.gov/pubmed/27578171
http://dx.doi.org/10.1038/srep32269