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Biosimilar structural comparability assessment by NMR: from small proteins to monoclonal antibodies
Biosimilar drug products must have a demonstrated similarity with respect to the reference product’s molecules in order to ensure both the effectiveness of the drug and the patients’ safety. In this paper the fusion framework of a highly sensitive NMR fingerprinting approach for conformational chang...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006049/ https://www.ncbi.nlm.nih.gov/pubmed/27578487 http://dx.doi.org/10.1038/srep32201 |