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Effect of BI-1 on insulin resistance through regulation of CYP2E1

Diet-induced obesity is a major contributing factor to the progression of hepatic insulin resistance. Increased free fatty acids in liver enhances endoplasmic reticulum (ER) stress and production of reactive oxygen species (ROS), both are directly responsible for dysregulation of hepatic insulin sig...

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Detalles Bibliográficos
Autores principales: Lee, Geum-Hwa, Oh, Kyoung-Jin, Kim, Hyung-Ryong, Han, Hye-Sook, Lee, Hwa-Young, Park, Keun-Gyu, Nam, Ki-Hoan, Koo, Seung-Hoi, Chae, Han-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006057/
https://www.ncbi.nlm.nih.gov/pubmed/27576594
http://dx.doi.org/10.1038/srep32229