Weibel-Palade body size modulates the adhesive activity of its von Willebrand Factor cargo in cultured endothelial cells

Changes in the size of cellular organelles are often linked to modifications in their function. Endothelial cells store von Willebrand Factor (vWF), a glycoprotein essential to haemostasis in Weibel-Palade bodies (WPBs), cigar-shaped secretory granules that are generated in a wide range of sizes. We...

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Detalles Bibliográficos
Autores principales: Ferraro, Francesco, Mafalda Lopes da, Silva, Grimes, William, Lee, Hwee Kuan, Ketteler, Robin, Kriston-Vizi, Janos, Cutler, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006059/
https://www.ncbi.nlm.nih.gov/pubmed/27576551
http://dx.doi.org/10.1038/srep32473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006059/
https://www.ncbi.nlm.nih.gov/pubmed/27576551
http://dx.doi.org/10.1038/srep32473

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