Cargando…

Fragment C Domain of Tetanus Toxin Mitigates Methamphetamine Neurotoxicity and Its Motor Consequences in Mice

BACKGROUND: The C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) is a nontoxic peptide with demonstrated in vitro and in vivo neuroprotective effects against striatal dopaminergic damage induced by 1-methyl-4-phenylpyridinium and 6-hydoxydopamine, suggesting its possible therapeutic p...

Descripción completa

Detalles Bibliográficos
Autores principales: Mendieta, Liliana, Granado, Noelia, Aguilera, José, Tizabi, Yousef, Moratalla, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006194/
https://www.ncbi.nlm.nih.gov/pubmed/26945022
http://dx.doi.org/10.1093/ijnp/pyw021